This manual, designed as a practical 12-step checklist, provides guidance on the selection and procurement of quality rapid diagnostic tests (RDTs) for malaria. Drawing on the results of the WHO/TDR-FIND-CDC Product Testing Programme, the manual aims to strengthen the capacity of national and international procurement officers. It covers all aspects of the procurement cycle, with special emphasis on product specifications, selection criteria for different epidemiological settings, different quantification methodologies based on malaria surveillance and consumption data, as well as quality control through lot testing.